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Phnshp45

Webb24 maj 2016 · In particular, the pHNSHP45 3 is the only one mcr-1-carring plasmid with known genome sequence prior to our study. Unlike the other mcr-1 -positive plasmid pKH457-3-BE 2 that is from the cattle isolate in Belgium and has the plasmid signature of IncP, both pHNSHP45 3 and pWH12 are hosted by E. coli isolated from swine in China, … WebbColistin resistance gene mcr-1 and pHNSHP45 plasmid in human isolates of Escherichia coli and Klebsiella pneumoniae. Colistin resistance gene mcr-1 and pHNSHP45 plasmid …

A Multidrug-resistant Monophasic Salmonella Typhimurium Co …

Webb17 jan. 2024 · IncHI2 plasmids, such as pHNSHP45–2, have been frequently associated with global spread of mcr-1 genes (3,13,14). Figure 1 Sequence comparison of scaffolds (portions of genome sequences reconstructed from end-sequenced whole-genome clones) identified in mcr-1 –positive plasmids pHNSH36, pHNZ319S, and pHNSH138 with 2 mcr … WebbThe Lancet Infectious Diseases 2016 16, 283-284DOI: (10.1016/S1473-3099(16)00012-8) 21 Blast comparison with pHNSHP45 showed 100% similarity only in a short, 2604 bp region that included mcr-1 (1626 bp) and a truncated ISApI1 mobile element that did not include the transposase encoding rural healthcare access https://turbosolutionseurope.com

Associations between human bacterial pathogens and ARGs are …

Webb4 apr. 2024 · Alignment of pEC-PAG-733 and pHNSHP45 (accession KP347127.1) produced using MAUVE software. History. Usage metrics. Read the peer-reviewed … Webb5 juli 2024 · pHNSHP45 was used as a reference to compare with the pMCRs described here and with other IncI2 plasmids. The outer circle with red arrows indicates annotation of the reference sequence. Gaps in the inner circles are missing regions when compared with the reference. Plasmids characteristics are included in Table 3. Webb16 okt. 2024 · Newport strains ASGD2 to pHNSHP45-2 revealed that this plasmid aligned very well with pHNSHP45-2 except that a region containing the tra genes, which were … sceptical in spanish

Emergence of plasmid-mediated colistin resistance ... - The Lancet

Category:Genome sequence and characteristics of plasmid pWH12, a …

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Phnshp45

Microorganisms Free Full-Text Mobile Colistin Resistance …

Webb5 juli 2024 · pHNSHP45 was used as a reference to compare with the pMCRs described here and with other IncI2 plasmids. The outer circle with red arrows indicates annotation … Webb27 feb. 2024 · The impact of plasmids pHNSHP45, pHNSHP45-2, pHNSHP23, pHNSHP17 and pHNSHP24 on host fitness was evaluated by direct competition assays of plasmid-carrying E. coli DH5α against plasmid-free E. coli DH5α. The transformants with pHNSHP45(IncI2) or pHNSHP23(IncX4) outnumbered the parent E. coli DH5α strain …

Phnshp45

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Webb16 okt. 2024 · Newport strains ASGD2 to pHNSHP45-2 revealed that this plasmid aligned very well with pHNSHP45-2 except that a region containing the tra genes, which were responsible for conjugation, was absent ... http://www.cpam-cmi.com/article/imagetext-detail/630

Webbthat plasmid pHNSHP45 exhibited an in vivo transfer rate between different E. coli strains (measured at 10–1 to 10–3 per recipient) (7), a feature that could contribute to the suc - cessful dissemination of the mcr-1 gene. Similarly, in our study, we can also confirm the transfer of the mcr-1 gene WebbColistin resistance gene mcr-1 and pHNSHP45 plasmid in human isolates of Escherichia coli and Klebsiella pneumoniae Lancet Infect Dis . 2016 Mar;16(3):285-6. doi: 10.1016/S1473-3099(16)00010-4.

Webb18 feb. 2016 · amino acid product encoded in pHNSHP45) (Fig. 1). It is also possible that a single SNP upstream of mcr-1 (-36) in pE0G430-1 may affect expression of the gene. … WebbDOI: 10.1016/S1473-3099(16)00010-4 Corpus ID: 36290610; Colistin resistance gene mcr-1 and pHNSHP45 plasmid in human isolates of Escherichia coli and Klebsiella …

WebbOne mcr-1-carrying Salmonella enterica serovar Indiana strain D90, was identified from 1320 Salmonella enterica isolates from poultry slaughterhouse in 2012 in China. The …

Webb27 juni 2024 · For instance, a 222.3-kb section of pWJ1 (85.4% of the total sequence) exhibited high similarity to the corresponding region of the 251-kb plasmid pHNSHP45-2 from E. coli strain SHP45, from which the first mcr-1 gene was identified . pWJ1 and pHNSHP45-2 had 12 resistance genes in common (Fig. 1A), while pWJ1 appeared to … rural health care indianapolisWebb27 feb. 2024 · Fitness Effects of mcr-1 Gene and mcr-1 Plasmids in Vitro. The impact of plasmids pHNSHP45, pHNSHP45-2, pHNSHP23, pHNSHP17 and pHNSHP24 on host fitness was evaluated by direct competition assays of plasmid-carrying E. coli DH5α against plasmid-free E. coli DH5α. The transformants with pHNSHP45(IncI2) or … rural health care center indianapolisWebb18 nov. 2015 · To identify the gene responsible for polymyxin resistance, pHNSHP45 was completely sequenced, which revealed a plasmid 64 015 bp in size with an average GC content of 43·0%. pHNSHP45 contains 60 predicted open reading frames and possesses a typical IncI2-type backbone (57 624 bp) encoding replication, horizontal transfer, … rural health care coordinationWebbGao, R., Wang, Q., Li, P., Li, Z., & Feng, Y. (2016). Genome sequence and characteristics of plasmid pWH12, a variant of themcr-1-harbouring plasmid pHNSHP45, from ... rural healthcare cdcWebb6 feb. 2024 · Except for a 3,684 bp region that was also present in a pHNSHP45-2-like plasmid and included the ISApl1 and mcr-1, the entire nucleotide sequence showed … sceptical mocking danwordWebbConclusion: This study reported a the multidrug-resistant Salmonella 4, [5],12:i:- isolate harboring mcr-1, blaCTX-M-14 and fosA3 from human for the first time in China. The … sceptical hindi meaningWebb17 jan. 2024 · IncHI2 plasmids, such as pHNSHP45–2, have been frequently associated with global spread of mcr-1 genes (3,13,14). Figure 1 Sequence comparison of scaffolds … sceptical mocking