Ints6
Integrator complex subunit 6 is a protein that in humans is encoded by the INTS6 gene. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA … WebMar 20, 2015 · This study identifies the putative tumor suppressor INTS6 and its pseudogene INTS6P1 in HCC through the whole genome microarray expression. …
Ints6
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WebMar 5, 2024 · INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling. Ding X, Chen T, Shi Q, Nan P, Wang X, Xie D, Li JDing X, et al. Exp Cell Res, … WebPseudogene INTS6P1 regulates its cognate gene INTS6 through competitive binding of miR-17-5p in hepatocellular carcinoma. Patents Method and Device for Statistical Tissue Sampling using Microdevices
WebNov 2, 2024 · Loss of INTS6 results in resistance to tumor cell death mediated by CDK9 inhibition, decreased turnover of CDK9 phospho-substrates, and amplification of acute oncogenic transcriptional responses. Pharmacological PP2A activation synergizes with CDK9 inhibition to kill both leukemic and solid tumor cells, providing therapeutic benefit … Webrates. Mechanistically, INTS6 increased WIF-1 expression and then inhibited the Wnt/β-catenin signalling pathway. Conclusion: The results of our study show that down-regulated INTS6 expression is associated with a poorer prognosis in HCC patients. This newly identified INTS6/WIF-1 axis indicates the molecular mechanism of HCC and
WebCRISPR (DepMap Public 22Q4+Score, Chronos) UBE2F SNAP23 CYB5A ADSL INTS6 MBTPS1 SCAP GET3 CYB5R3 GRB2 RNAi (Achilles+DRIVE+Marcotte, DEMETER2) MED14 CENPT CAGE1 ICE2 DYNC1LI1 ANLN ENDOV CCNK KIFC3 WebC-terminus of INTS6 (supplementary material Fig. S3). These results further confirm that the N-terminus of INTS3 interacts with hSSB1 and the C-terminus of INTS3 directly binds to …
WebMar 5, 2024 · INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling. Downregulation of Wnt/beta-catenin signaling was observed during the …
WebOct 15, 2024 · The expression of INTS6 in these malignancies was downregulated [14,15,19]. Besides, INTS6 inhibited cell growth via modulating Wnt signaling pathway in … great white shark off myrtle beachWebSignalway Antibody, strives to supply a range of antibodies, especially phospho-specific antibodies for cell signaling transduction research, Methylated/Acetylated antibodies, proteins and other reagents for research with the best quality and competitive price. Discover more research tools for life science. florida state university nutrition programWebБәхәс:INTS6. Бәхәс. : INTS6. Бу мәкалә тематикасы «Биология» википроекты белән бәйле. Аның максаты — темалары буенча Биология белән бәйле мәкаләләрне төзү һәм яхшырту. Теләсәгез, мәкалә өстендә ... florida state university nursing schoolWebImmunohistochemistry-Paraffin: INTS6 Antibody (3D9) [H00026512-M02] - Analysis of monoclonal antibody to DDX26 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml. Sandwich ELISA: INTS6 Antibody (3D9) [H00026512-M02] - Detection limit for recombinant GST tagged INTS6 is 0.1 ng/ml as a capture antibody. great white shark open oceanWebApr 13, 2024 · 为了评估ints6 / pp2a缺失对cdk9抑制诱导的新生转录抑制的影响，研究团队在ints6敲除的细胞中进行了4-硫尿苷代谢标记，然后进行rna测序。他们发现ints6的丧失导致对cdk9抑制介导的肿瘤细胞死亡的抵抗力，cdk9磷酸底物的周转率降低以及急性致癌转录反 … great white shark off jersey shoreWebNov 11, 2009 · Background The gene encoding integrator complex subunit 6 (INTS6), previously known as deleted in cancer cells 1 (DICE1, OMIM 604331) was found to be frequently affected by allelic deletion and promoter hypermethylation in prostate cancer specimens and cell lines. A missense mutation has been detected in prostate cancer cell … florida state university online mlisWebA record-breaking number of visitors was counted at Cinte Techtextil China held in Shanghai from September 1st to 3rd.The heavy rain did not dampen visitors' e florida state university online doctorate