WebMar 13, 2024 · Adequate hydration with administration is essential. SEIZURES: Seizures related to plasma mineral and electrolyte changes reported. Monitoring for such changes (and potential sequelae) is recommended. Mineral and … WebThe most important adverse effect of foscarnet is nephrotoxicity, but the renal function and pathological changes are reversible, as long as the fibrosis is not serious and the patient receives enough hydration. 18 We selected patients with good allograft function (the eGFR >45mL/min/1.73m 2) to be treated with foscarnet therapy and given 1000 ...
Foscarnet Intravenous: Uses, Side Effects, Interactions ... - WebMD
WebApr 22, 2024 · Foscarnet sodium is a white, crystalline powder containing 6 equivalents of water of hydration with an empirical formula of Na 3 CO 5 P · 6H 2 O and a molecular weight of 300.1. The structural formula is: Foscarnet sodium injection has the potential to chelate divalent metal ions, such as calcium and magnesium, to form stable coordination ... WebFoscarnet is administered by slow intravenous infusion. Do not administer by rapid IV infusion or by direct IV injection. Monitor renal function and adjust doses accordingly. … joey song meaning
Foscarnet Sodium (Sagent Pharmaceuticals): FDA Package Insert
WebHydration is recommended to reduce the risk of nephrotoxicity. Infuse 750-1000 mL of normal saline prior to the first infusion of foscarnet to establish diuresis. With subsequent infusions, 750-1000 mL of hydration fluid should be given concurrently with each 90-120 mg/kg infusion of foscarnet. WebFoscarnet. Nephrotoxicity; Seizure Risk. Nephrotoxicity. Renal impairment is the major toxicity of foscarnet sodium injection. Frequent monitoring of serum creatinine, with dose adjustment for changes in renal function, and adequate hydration with administration of foscarnet injection, is imperative. WebFoscarnet (trisodium phosphonoformate hexahydrate) is a pyrophosphate analogue that interacts with the enzymatic action of polymerases and inhibits the cleavage of pyrophosphate from the nucleoside triphosphate. Because of this mechanism, the antiviral activity of the drug is broad. intel 12th gen processor naming scheme